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Rheumatoid Arthritis Gene Mutations

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New research shows that people who are at risk for rheumatoid arthritis are much more likely to develop the disease if they smoke cigarettes.

In a new study, Swedish scientists have analyzed the interaction between the major genetic risk factor for rheumatoid arthritis—a gene mutation called the shared epitope—and the environmental risk factor smoking.

Among those with the gene mutation, smokers were more likely to develop rheumatoid arthritis than nonsmokers. The take home point is that smoking and the gene mutation are a dangerous combination. Smokers with the gene mutation were five to fifteen times more likely to have rheumatoid arthritis than people at no risk for disease.

Source: genomenewsnetwork
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