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What Do These Terms Mean: Inhibitor, Antagonist, Agonist?

Hi all. It's me once again. LOL

I am just wondering if someone would please be so kind as to explain to me in layman's (sp?) terms what the words in the subject title actually mean in regard to psychitry. Also what about CYP-2D6 and CYP-3A4?

My new medication, Invega (Palperidone) says the following and I'd just like to know a bit more about what I'm reading and taking:

DA2 antagonist
5-HT2A antagonist
NE alpha-1 antagonist
NE alpha-2 antagonist
H1 antagonist

Half-Life & Metabolism:
23 Hours

I believe that DA2 is a kind of Dopamine, 5-HT2A is some type of Serotonin, NE Alpha 1 & 2 are some kinds of Norepinephrine and H1 is a type of Histamine.

But in all honesty I really don't know much about this stuff. Can ya tell? LOL So if anyone would be so kind as to please enlighten me I'd be most thankful. I really would like to know more about what I'm putting into my body and what it's doing in there.

Thanks again. Smile

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replied February 6th, 2019
Thank you for asking at Ehealth forum!

I read your question and I understand your concern.
CYP are cytochrome, which are liver enzymes invlove in metabolism of drugs or toxins that are inhibited or induced by drugs. Those drugs that inhibit it ,their concentration increase and those drugs that induce it,their concentration decrease.
Inhibitors mean blockers. Antagonist means drug that block receptor while agonist stimulate it.
I hope it helps. Stay in touch with your healthcare provider for further guidance as our answers are just for education and counselling purposes and cannot be an alternative to actual visit to a doctor.
Take care
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