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Rh- blood type & IVF (in vitro fertilization)

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My question is about being rh negative, I am actually going thru in vitro right now and have been reading things that are freaking me out. I had an abortion when I was 18 and found out I was a negative and received a immuneglobulin shot. When I was 20 I had a miscarriage and never received the shot, so now I read that I have already may be sensitized, which I guess that means I would not receive the globulin shot at 28 weeks pregnat and because I did not receive that shot how much more does that put me at risk and risk of what. And what would the most likley procedure of my condition would there be, and also are the treatments for this very sucessful and am I worrying to much for nothing.

One more question is what is the best treatment for panic attacks while pregnat. I barley ever take my ativan but my comfort is knowing I can. What would be the comfort drug while I am pregnat without having to take something everyday?


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replied March 26th, 2007
Pregnancy Answer A2513
It seems that the assisting doctors made a mistake by NOT giving you the anti-Rh immunoglobulin shot when you miscarried 10 years ago. Rh-sensibilisation happens in Rh- mothers during delivery, miscarriage or abortion of an Rh+ baby/fetus when the erythrocytes from the fetus enter the mother’s circulation. If the baby is Rh-, sensibilisation won’t occur. We can’t be always certain if a baby/fetus is Rh+ or Rh-, so an anti-Rh immunoglobulin shot is always administered to an Rh- mother who has delivered, miscarried or aborted. An anti-Rh immunoglobulin shot can prevent Rh sensibilisation only if the shot is given just before or after delivery, miscarriage or abortion. The shot must be administered within 72 hours after any of these procedures. After sensibilisation, the mother’s immune system acquires the ability to create anti-Rh antibodies that destroy Rh+ erythrocytes. During the first pregnancy with a Rh+ child, sensibilisation happens at the end of the pregnancy so there is not enough time or amount of anti-Rh antibodies created to damage the fetus.... but during the next pregnancy with Rh+fetus, the antibodies will be created much faster and in greater amount so fetal damage will probably happen.
At this time, your blood should be tested for the presence of anti-Rh antibodies. The presence of anti-Rh antibodies in your blood is secure proof that you were sensibilised 10 years ago. Lack of anti-Rh antibodies, however is not enough evidence to prove that you were not sensibilised... because the antibodies expire over time but the ability for their reproduction remains. You can get pregnant but your blood should be monitored for anti-Rh antibodies during pregnancy. Ultrasound scans and amniotic liquid checks for bilirubin level should be done regularly.

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