Medical Questions > Mental Health > Depression Forum

Physical Symptoms W/ Depression??

Must Read
Do you know how doctors define clinical depression? Learn more about this brain disorder and types of depression that doctors diagnose here....
Can depression run in families? Can hormones really make you depressed? Yes! Learn more about causes and conditions of clinical depression here....
People with depressive illnesses do not all experience the same symptoms. Do you know the signs and symptoms of depression? Read on to learn more....
I have been having burning skin and aches all over for almost a year now off and on. I started on zoloft back in september and the burning went away. Therefore, I wonder if the burning was brought on by depression and anxiety. It went away for about 2 months only to return before christmas. The fact that it did go away after starting the zoloft makes me wonder if it's not an anxeity/stress thing.

Has anyone here ever experienced physical pains w/ their anxiety/depression?

Thanks so much!

Did you find this post helpful?

replied February 21st, 2004
Depression Is Linked to Other Physical Diseases

hundreds of studies have shown a link with depression and other diseases.
The reason.
Depression is categorised by excess levels of a hormone called pge2 in your body.
This hormone (an eicosanoid) is linked to all the major western diseases.
Other "bad" eicosanoids called leukotrines can cause a variety of skin disorders and asthma.
Pge2 mediates pain so could certainly explain your aches.
You can control your balance of "good" and "bad" eicosanoids through diet and lifestyle.

I hope this excerpt taken from the book from depression to glorious health (free download at http://www.Geocities.Com/glorioushealth ) is useful to you.

Kindest regards,
andrew cavanagh

eicosanoids are your body’s “master hormones”. They indirectly control nearly every function of your body. Depression is linked to a “bad” eicosanoid called prostaglandin e2 (pge2).
A study in 1983 found that levels of the bad eicosanoid (pge2) were 2-3 times higher in patients with depression than in normal controls. Subsequent studies have also found elevated levels of pge2 in the bodies of patients suffering from depression.
This is alarming news because overproduction of the “bad” eicosanoid pge2 not only causes mood problems like depression. Pge2 also causes inflammation, suppresses your immune system, causes blood clotting and a host of other potentially deadly effects.
These can lead to serious disease in the following ways:

effects of the “bad” eicosanoid pge2:
 pge2 reduces the release and uptake of neurotransmitters in your brain like serotonin which can lead to depression.
 pge2 causes your blood to clot which can lead to heart attacks or strokes.
 pge2 causes your blood vessels to contract (vasoconstriction) which can lead to high blood pressure.
 pge2 depresses your immune system which can lead to cancer.
 pge2 stimulates pain and fever which can lead to allergies, headaches, arthritis and chronic pain.
 pge2 causes inflammation in your body and your brain which could lead to alzheimer’s disease and multiple sclerosis (ms).

So depression is often an early warning that more serious conditions like heart disease, stroke and cancer are developing. You simply can’t afford to take depression lightly. You must change your diet and lifestyle now to reverse the effects of depression and the other more serious effects of your body’s overproduction of “bad” eicosanoids like pge2.

The good news, good eicosanoid pge1
the good news is that you can control your body’s production of eicosanoids with diet and lifestyle. And when you do this often not only will your symptoms of depression abate or disappear many other long term health problems could also be relieved.
Like most hormones in your body the bad eicosanoid pge2 has an opposing hormone to help keep your body’s functions in balance.Pge2’s opposing hormone is prostaglandin e1 (pge1).

The good eicosanoid pge1 has many wonderfully beneficial effects:
 pge1 increases the release and uptake of neurotransmitters in your brain like serotonin increasing feelings of wellbeing and calmness.
 pge1 stops your blood from clumping, reducing the chance of heart disease and strokes.
 pge1 helps your blood vessels to relax reducing your blood pressure and increasing circulation.
 pge1 controls your immune system reducing the risk of cancer.
 pge1 reduces pain often leading to relief from headaches, arthritis and chronic pain.
 pge1 reduces inflammation in your body and your brain reducing the chance of diseases like ms and alzheimer’s.

To understand how to switch the production of eicosanoids in your body from bad to good you first need to understand three major hormonal systems in your body: eicosanoids, insulin and cortisol.

1.Eicosanoids are your body’s “master” hormones indirectly controlling nearly every function in your body including feelings of wellbeing and indirectly feelings of depression.
You need to increase your body’s production of “good” eicosanoids to stimulate feelings of wellbeing and reduce or eliminate feelings of depression.

2. Insulin is your body’s “sugar” hormone, released in response to blood glucose (blood sugar).
Excess insulin production in your body can be caused by eating a diet too high in carbohydrates. Especially carbohydrates which convert too quickly to blood glucose.
Excess insulin can stop the production of good eicosanoids and stimulate the production of bad eicosanoids.
This can lead to depression.
Excess insulin production also leads to the release of the “stress” hormone cortisol.

3. Cortisol, the “stress” hormone is released when you are under physical or emotional stress.
Cortisol can block the production of “good” eicosanoids leading to feelings of poor health and depression.
Also, long term exposure to excess cortisol can kill your brain cells, leading to impaired brain function.

So to reduce the symptoms of depression or to eliminate it altogether you need to do three things:
1. Increase your body’s production of good eicosanoids (the “master” hormones).
2. Control your body’s production of insulin (the “sugar” hormone).
3. Reduce your body’s production of cortisol (the “stress” hormone).

In this book you’ll learn how to do all that in these six steps. The six steps from depression to glorious health are:
1. Following a good diet.
Which increases your body’s production of “good” eicosanoids, controls your body’s insulin production and reduces the release of cortisol.
2. Drinking enough water.
Which allows all your body’s systems to function efficiently.
3. Exercising daily.
Which increases your insulin sensitivity (helping to control your body’s insulin production) and reduces your cortisol levels.
4. Practicing advanced hygiene.
Which helps to increase your body’s production of “good” eicosanoids and helps to reduce your body’s cortisol levels.
5. Improving the quality and quantity of your sleep.
Which helps to increase your body’s production of “good” eicosanoids and reduce your body’s cortisol levels.
6. Building good emotional health.
Which helps reduce your body’s cortisol levels.

Free download of the full from depression to glorious health in six steps at http://www.Geocities.Com/glorioushealth
Did you find this post helpful?

replied March 9th, 2004
Hello sherrydenise,
i am sorry to hear of your problems! I am wondering if you are having difficulty sleeping? I know if I do not get enough sleep for extended periods of time I often feel achy. Depression is linked with sleep disturbance - so this is why I ask. Also, you mentioned feeling like your skin is burning - do you develop any rash? It may be hives which are also associated with depression and anxiety and is often psychosomatic in nature, which is how your anxiety manifests itself physically. The tricky thing with psychiatric meds are that some work for an individual while others may not. Dosage may also be key here. Usually, these meds are used on a trial and error basis until the correct medication as well as the correct dosage is found for an individual. If all else fails, try for a second opinion from someone else. Good luck.
Did you find this post helpful?

replied March 12th, 2004
Extremely eHealthy
Burning skin & even aches could also be caused by a plain old allergy, it is possible to develop an allergy to something after years of using/eating/being near it so I suggest you try an anti-histamine & see if that helps at all, if it does then all you have to do is figuer out what is causing the allergy.

The aches though could also be that you're not sleeping properly, either due to the burning skin or maybe you need a new pillow, mattress or sleeping position.
Did you find this post helpful?

replied March 12th, 2004
Allergies And Eicosanoids
Burning skin certainly could be caused by an allergy.

It's important to note that allergic reactions are actually mediated by eicosanoids. Eicosanoids can cause an allergic reaction 5,000 times more potent than histamine.

I am a great believer in determining if you have any serious allergies. At home you can perform a simple arm test or better still see a medical specialist.

But keep in mind that since the allergic response is increased by bad eicosanoids you really need to deal with this problem with changes in diet and lifestyle.
Often minor allergies disappear when your eicosanoids are in balance.

Kindest regards,
andrew cavanagh
Did you find this post helpful?

User Profile
replied March 18th, 2004
Advanced Support Team
The only time I developed a rash or itchy spot was right after I started taking zoloft. And you said it stopped when you first started zoloft, so I have no clue really what it could be. I'd call your doc and let him know of the itching problem. Does something more stressfull happen to you right before you get the itchyness??
Did you find this post helpful?
Quick Reply
Answers to Similar Questions
User Profile
Dr. Nikola Gjuzelov
User Profile
Dr. Nikola Gjuzelov
User Profile
Dr. Nikola Gjuzelov
User Profile
Dr. Abhijeet Deshmukh
User Profile
Dr. Jeff Bailey