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Sore Breasts If Stop Taking Hormones

If I stop taking premarin, within a week my breasts get sore. I have gone as long as 3 weeks without premarin, but then go back on it due to my breasts being so sore. I don't want to take premarin anymore, but can't stand the soreness. Doctors don't know why this happens and don't have any answers. As soon as I start taking hormones again, it goes away. If I stay off hormones, will the soreness eventually go away?
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