When you have contracted this illness what is the progress of the disease
my aunt is currently receiveing blood transfusions & platelets every few days. How long can she live this way and what can we expect to happen
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replied January 19th, 2018
Thank you for asking at Ehealth forum!

I read your question and i understand your concern.
The natural history of myelofibrosus is of increasing bone marrow failure with transfusion dependent anemia and
organomegaly(e.g spenmegaly).
Aboyt 10% of cases develop aggressive form of acute leukemia.
Survival depends upon rsik factor.
Risk factots are age more than 65 years,constitutional symptoms
(fever,weight loss ,night sweats),hemoglobin less than 10 mg/dl,wbc count greater than 25000 and blast cells more than 10%.
If there are no risk factors median survival will be 11 years and if there are 3 or more than three risk factors then median survival will be as low as 2 years.

I hope it helps. Stay in touch with your healthcare provider for further guidance as our answers are just for education and counselling purposes and cannot be an alternative to actual visit to a doctor.
Take care
Khan
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