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Testicular Cancer Causes and Risk Factors

Testicular Cancer Causes and Risk Factors
Testicular Cancer
Causes and Risk Factors

What causes testicular cancer?
It is now yet known what exactly causes germ cells in the testes to become abnormal and develop into cancer. However, doctors have found that the disease may be linked to genetic problems, abnormal chromosomes and changes in the factors that regulate cell division and the cell cycle. For example, certain changes in chromosomes and DNA may cause normal testicular germ cells to develop into germ cell tumors. Specifically, doctors think that testicular germ cell tumors may form when something abnormal happens during the creation of sperm and cell division (meiosis). Instead of forming normal sperm cells with 23 chromosomes, all 46 chromosomes remain.

Risk factors
The exact cause of testicular cancer is not known. However, some men are more likely than others to develop testicular cancer. For example, testicular cancer is most commonly diagnosed in men between the ages of 18 and 32 and is approximately 5 times more common in Caucasians than African Americans. In fact, there are certain factors that seem to increase the risk for testicular cancer. Other risk factors for testicular cancer include:

Age - Testicular cancer usually occurs in young or middle aged men and is common among men between 15 and 40.

Body size - Tall, slim men may be at higher risk for developing testicular cancer.

Ethnicity -Testicular cancer is 2-5 times more common among Caucasian men than African-American or Asian-American men.

Family history - If a man has a brother or father who has been diagnosed with testicular cancer, he is at an increased risk to develop testicular cancer. Additionally, men whose mother took a hormone called DES (diethylstilbestrol) during pregnancy to prevent miscarriage are at greater risk of developing testicular cancer.

Medical conditions - Men infected with HIV or men who have been diagnosed with multiple atypical nevi (pigmented spots or moles located on the back, chest, abdomen, and face) may be at increased risk for testicular cancer.

Personal medical history – Men with a history of testicle problems such as undescended testicle(s), abnormal development of the testicles, Klinefelter's syndrome, or previous testicular cancer are more at risk of developing testicular cancer.

Profession - Testicular cancer seems to be more common among men with a white-collar occupation, which may be linked to a decreased level of physical exercise.

Socio-economic status - Testicular cancer seems to be more common among men from wealthier social groups.

Testicular cancer used to be considered a difficult and dangerous cancer, but early diagnosis and treatment of symptoms have greatly increased the survival rate of men diagnosed with testicular cancer. How can you tell if you experiencing testicular cancer, versus a less serious testicle problem? Read here to learn to identify the signs of testicular cancer next.

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Tags: Cancer, atypical nevi, american men, diagnosis, treatment, Pregnancy, caucasian, Exercise, infected, american, atypical, symptoms, african, abdomen, cells, sperm, asian, HIV, tumors, cancer family history
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