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taking Metphormin admittedly not like I'm suppose to. ..

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I am 26 and was diagnosed with PCOS in March 2012. I have not had a period since i stopped taking bc in February. I have been taking Metphormin admittedly not like I'm suppose to. Lately, I have been experiencing pregnancy symptoms such as fatigue, pinkish-brown discharge, severe lower back pain, mood swings, constipation, flu like symptoms and 1 day of bleeding despite not having a period in over 8 months. Those are just to name a few symptoms but there has been several more. I took 2 hpt and they were both negative. I went to the dr and they gave me a urine test which was also negative. I requested a blood test but they never did it. Could I really be pregnant? Do you have any suggestions about requests I should make of my dr.?


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replied January 31st, 2013
Early Pregnancy Signs and Symptoms Answer A41953
Welcome to e health forum.

The symptoms you have been having are nonspecific and cannot be attributed to pregnancy.

The chances of you being pregnant with 2 pregnancy tests negative, is very less likely.

First you need to understand the condition you have, PCOD and the methods used to treat it. Lack of proper information about the condition, causes women, think that the condition is short lived and taking medications for a few days, will completely cure it.

PCOD ( polycystic ovarian disease) is one of the commonest causes of infertility. Patients have multiple small cysts in their ovaries that occur when the regular changes of a normal menstrual cycle are disrupted. The ovary is enlarged; and it produces persistently elevated amounts of androgen and estrogenic hormones , which set up a vicious cycle. This excess, along with the absence of ovulation, may cause infertility.

Obesity also can aggravate PCOD because fatty tissues are hormonally active and they produce estrogen which disrupts ovulation. Overactive adrenal glands can also produce excess androgens, and these may also contribute to PCOD. Insulin resistance is also a major factor in obese women with PCOD.

Correction of PCOD needs the following interventions:

1. WEIGHT LOSS: A permanent weight loss plan via a low calorie diet (obtained by consulting a dietitian) as well as a good exercise plan will be very effective. Note that Crash diets are usually not effective.

2. PHYSICAL EXERCISE : A good exercise plan, including aerobic activities such as walking, jogging or swimming are advised. Try to find a partner to do this with, so that you can help each other to keep going.

The management in the infertile patient will usually focus on inducing ovulation to help them conceive with medications . Some of the following medications or a combination of the medications are essential to bring on proper ovulation cycles.

A. Ovulation inducers - like clomiphene , HMG (gonadotrophins) and Letrozole

B. Metformin (a antidiabetic ) - helps to correct the insulin resistance, which is a major factor, especially in obese patients with PCOD.

In cases that do not respond to the above measures intra uterine insemination or invitro fertilization techniques would be the alternative to achieve conception.

The good news is that with the currently available treatment options, successful treatment is usually possible in the majority of patients with PCOD. But this would need patience to work and follow the doctors advice and compliance with medications that are prescribed. Irregular medication use or Abrupt stopping of medications will not result in controlling the condition.

I would advice you continue to work with your gynecologist and define your proper goal of therapy.

I hope this helps.


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