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Suggested Provera drug therapy and its side effects

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I have been having irregular periods with my last being on May 2nd and my ARNP prescribed medroxyprogesterone 10mg for 10 days on May 21st. I was hesitant about taking it because I weary of any kind of drug. I didn't take it and my cycle started on June 2nd and last about 3 days (normally 5-7 days; time between cycles varies also between 27 and 34 days). After researching I have decided to go ahead and take the progesterone. Should I start taking it right away or wait till approximately day 16 of my cycle?

My husband and I are trying to have our first child so we want to do what's best.

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replied June 8th, 2009
Fertility Answer A6741

One of the conditions medroxyprogesterone tablets are used for is abnormal uterine bleeding due to a hormonal imbalance in the absence of organic pathology. According to the data you provided, there is a big possibility that the doctor actually recommended the medroxyprogesterone to treat this condition in you.

Beginning on the calculated 16th or 21st day of the menstrual cycle, 5 or 10 mg of Provera (generic name: medroxyprogesterone)may be given daily for 5 to 10 days. To produce an optimum secretory transformation of an endometrium that has been adequately primed with either endogenous or exogenous estrogen, 10 mg of Provera daily for 10 days beginning on the 16th day of the cycle is suggested. Progestin withdrawal bleeding usually occurs within three to seven days after discontinuing therapy with Provera.

However, you might want to talk to your gynecologist to check if Medroxyprogeasterone is best for you, or other medications would be better, because you want to conceive and Medroxyprogesterone is not recommended for use in pregnancy, since there may be increased risks for hypospadias, clitoral enlargement, and labial fusion in children whose mothers are exposed to Provera during the first trimester of pregnancy.

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