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Stomach pain not from ulcer or acid reflux (chronic pain?)

I have had ongoing stomach problems for years, started off on Nexium so I could take Panefen Plus for extreme period pain ( I had already been taking it extensively before going on Nexium). The Nexium was to aid my discomfort when taking Panefen which I believe was what started my stomach problems. After a year the Nexium started to wear off. Pain in my stomach got worse due to growing anxiety and depression, was put on Codeine for pain but as I am now sensitive to anything with Codeine or Ibuprofen, it did not help. Then was put on Rabeprazole. That helped a little but the pain came back.

I have been put on and was successfully using Paroxetine Sandoz to treat depression and anxiety, sometimes the stomach pain came back while on it and it was a persistent, pressing pain which made me feel incredibly uncomfortable. I came off Paxil and tried Pristiq. Didn't work for my mental health problems so I came completely off all medications and then started on Lyrica and after 2 weeks went back on Paxil.

The pain resolved it self up until a month ago, I ate food with chilli on it and that completely set me off. I now have the pain back, nothing much helps. I tried Paracetemol which helped a little and came off Paxil. I'm not having any luck with the doctor, she doesn't know what the problem is after blood tests, xrays, ultrasound, ct scan and endoscopy. All these came back clear.

I'm not sure what to do.
My doctor put me on Fluoxetine, I only took one as the morning after (5am) I woke up with worse pain and it prevented me from sleeping.
The pain is constant and that's what hurts so much, it is not 10/10. I'd say it's 6/10 but the constant feeling of it is making me more anxious and depressed. It is stopping me from sleeping properly. I was making good progress with my anxiety and now I have gone backwards, I am no longer getting out of the house to volunteer and it is impacting my quality of life.
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replied November 11th, 2014
Hello and Welcome

I appreciate your concern

The nexum or PPIs should be used in a higher dose to counter GERD and dyspepsia. sucralfate and Bismuth subsalicylate addition will get an additive effect.
I would empirically recommend a two week course of a
course of A PPI like Esomeprazole and a prokinetic
like metoclopramide to see for improvement, if
symptoms persist then an endoscopy would have been appropriate.
IBS was also treated as it does have a link as antidepressants were also used

I would suggest you consult a psychiatrist
so that a Mini mental state exam is performed.
to ascertain depression and or anxiety,
Meds can be adjusted afterwards in addition
to cognitive behavioral therapy. Yoga and meditation , too have proven benefit
in addition to relaxing exercise.

wishing you best of health


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