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side effects of taking glutathione

The side effects of taking glutathione depend on the form you are taking it in, and the side effects maybe direct or indirect.

Drugs that are precursors (building blocks) for glutathione.
Some include S-Adenosyl-Methione, which is expensive and can cause gastrointestinal problems, while ornithine decarboxylase, procyteine, and oxothiazolidine carboxylate both are enzymes and limited in their production of GSH in the body.

The most used and familiar drug is N-acetyl-cysteine (NAC), which is a powerful precursor of glutathione. As a drug it works extremely quickly, and is very effective, but has significant side effects, which include its efficacy or usefulness peaks very quickly, and has to be administered several times per day, which causes toxicity. This is a direct glutathione side effect.
vitamin E, and other micronutrients, are included in the substances called co-factors.

Selenium is a component of the enzyme glutathione peroxidase. Selenium functions mainly as an antioxidant, and works synergistically with Vitamin E. It is plentiful in plants and meats and supplementation is not usually necessary, but dosages of between 25-50mcg/day are recommended.

Side effects of over doses occur around 400 mcg/day and include hair loss, numbness or tingling in the fingers or toes, and white spots on fingernails and toenails. Selenium overdose leads to an indirect glutathione side effect.

Both B1 and B2 are essential and maintain GSH at its optimal capacity. Dosages between 50-150mg are suggested, while higher levels appear to show no side effects.

Vitamin C also known as ascorbate and ascorbic acid, has a long list of properties, but is also an antioxidant that works synergistically with E, and the other co-factors to allow GSH to work effectively. Dosages up to 2000 mg can be tolerated, and side effects of over dosages can lead to diarrhea and cramps. An indirect glutathione side effect.

B6, B12, play an indirect, yet important role in glutathione metabolism, while folic acid works with B12 in amino acid metabolism and protein synthesis. Dosages of 10-50mg of B6, 10-50mcg of B12, and 400mcg of folic acid are recommended per day.

Like selenium Vitamin E is an antioxidant, a detoxifier, and helps to keep glutathione in its reduced (non-oxidized) state. Dosages up to 400IU are recommended and excessive intake can be toxic creating gastrointestinal and neurological side-effects.
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First Helper ayurveda

replied January 27th, 2011
I think the best solution to whiten anyone's dark skin is Met Tathione

(reduced glutathione). In just two weeks, you'll see the difference of

having evenly toned, radiantly whiter skin. It works for me. They also have the met tathione vitamins

and soap products. They also ship outside the philippines.
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replied March 30th, 2011
Give some advice please
@Jaycoblee: hey, i also wanted to try met tathione in d next week or two. Would you giv me some advice on how to use it. Of course u take it orally, but how many times a day. Is it after meal? And in what time daily basis? afternoon, night, midnight approximately what time? Any answer would be appreciate it. Thanks in advane.
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replied August 21st, 2012
Alternative to Glutathione Injection
Injections goes to your blood then Kidney. Glutathione should be stored in liver. Met Tathione is not glutathione. I've been trying this product and there's a big difference in 10 days Smile if you like whitening you just take 2 sachets per day. Name of the product is Glutasome.
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