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Hello, I am a 38 y. o. woman in good health and i do not take any medication. About 1 year ago I started reacting violently to foods that are high in Tyramine like salami, cheese, sauerkraut, marzipan, avocado etc... I've had about 12 attacks in 2 years and the symptoms are always the same : about 10 mn after ingesting 2 slices of salami my heart starts racing ( 130 to 150 bpm for 5 to 10 mn), my blood pressure goes up, I feel very dizzy and nauseous and my whole body starts shaking for about 30 mn, which is usually followed by a light headache. I was checked for food allergies it was determined that my only allergy was seafood which of course I avoid.
None of the doctors I've seen could tell me why i became so sensitive to tyramine and if it was a temporary condition. I put myself on a low tyramine diet and I am less terrified of eating as i haven't had an attack in a month. Have you ever seen a patient with the same strange symptoms ? Thank you for your time. Sophie


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replied April 30th, 2009
Digestive and Bowel Disorders Answer A6465
Tyramine is known to cause migraine headaches in susceptible individuals. Rarely, hypertension and headaches, and other signs of autonomic nervous system stimulation, can be provoked by tyramine in patients with a rare adrenal tumor known as a pheochromocytoma, or in patients with an overactive thyroid gland. Also, some medications, when combined with tyramine, can also cause the kinds of reactions that you describe (the most common drugs associated with this interaction are antidepressants in the monoamine oxidase, or MAO, inhibitor class).

Robert A. Wascher, MD, FACS
A landmark, evidence-based guide to a healthy cancer-prevention lifestyle, based on cutting-edge cancer research.
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