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positive urine pregnancy test office and a negative blood?

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I am very upset at the moment because last month my period was a week early and very weird, nothing but spotting for seven days. Then on January 2, 2012 I went to my primary doctor to have a pee test done for pregnancy and it was negative. So this past week I was still exhibiting pregnancy symptoms so I went to my OBGYN on Tuesday the 10th of this month. She took a pee test in her office and then came in saying I was indeed pregnant. She did an transvaginal ultrasound and said she could see the sac, (it was very tiny). She then prescribed me prenatal vitamins and told me to go get some blood work done. I had a blood test done and she called with the results this morning and said that the blood test came back negative and I was not pregnant. My question is how can I have a positive urine pregnancy test in her office and a negative blood test in the same day? Is there any way I could still be pregnant? I am still exhibiting many pregnancy symptoms even as me speak. Could I still be preg?

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replied January 15th, 2012
Am I Pregnant Answer A30435
Hi, and thanks for your medical question on eHealth forum!

Yes, this is a confusing scenario. Either the urine test was false positive or the blood HCG test was false negative. The blood HCG test can become false negative under the hook effect where one HCG variant overshadows the other. In such cases blood dilution followed by retesting usually gives a positive result. You can discuss this aspect with your gynecologist. Also you can undergo a tansvaginal ultrasound at 7 completed weeks since your last periods. This may be able to give a more clear picture. Hope this helps. Take care!

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