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Normal blood tests and enlarged spleen

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i have an enlarged spleen with normal blood work, recently i went on a PPI for GERD which has gotten rid of several symptoms but has also isolated a few. i am unable to sleep on my right side or my back without having breathing problems. if i do sleep on that side i wake up with pain in my stomach. also i have shortness of breathe. my doctor isn't aware of any condition that could cause normal bloodwork with the spleen, so she is waiting a month before seeing me again. i am afraid that this is too long to wait without seeing a specialist. i wonder if my pain and shortness of breathe can be linked to something with normal blood work or could it be that a deaper testing of the blood is needed? and should i request a quicker appointment? i am afraid they are missing something and if i wait too long it could be too late to treat. thank you


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replied February 8th, 2010
Spleen Answer A9846
Hi and welcome to the forum! I am glad that I can help you.

You would like to know whether you have any medical condition when you experience a normal blood test and an enlarged spleen.

The spleen may be enlarged in several conditions such as infections, heart disorders (like chronic right chamber failure), hematological issues (leukemia, anemias excluding the iron deficit anemia), etc. In infections neutrophils (type of leukocytes) will be increased if there is bacterial infection and lymphocytes will be increased if there is viral infection. In mononucleosis mononuclecytes are increased due to viral infection with the Ebstain-Barr virus. In right chamber failure of the heart additional symptoms like chest pain, headache due to increased blood pressure, palpitations, exhaustion, enlargement of the liver and spleen (pain under both sides of the rib cage) and edemas on legs may appear. In hematological conditions like leukemia the number of lymphocytes will be increased, individuals may experience frequent infections and anemia. In all the other types of anemias that appear due to destruction of the erythrocytes the spleen is enlarged and there could be increased bilirubin in the blood.

Given the data that you described, you may be experiencing an enlarged spleen with normal blood tests. See a hematologist to rule out any blood- related diseases that may cause enlargement of the spleen. You may also consider seeing a cardiologist to rule out heart conditions.

Please keep in mind that I provide medical information only. I am not able to diagnose medical conditions online. Please contact your doctor or other qualified healthcare provider such as a hematologist and a cardiologist for further advice and information about diagnosis and treatment of your current condition.


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