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Non-Hodgkin's Lymphoma, Diffuse Large B-cell Lymphoma

My father is suffering Non-Hodgkin's Lymphoma, Diffuse Large B-cell Lymphoma (DLBCL) since Sep 2009.

More infomation for his disease is as following:

Period: IV-A.

Position: Both sides of adrenal gland. (Currently only one left)

Current Treatment:R-CHOP for 8 times (already).

My father is 54 years old.

My question is:

After the eighth chemotherapy, the SUV of PET CT has extremely increased from 5.0 to 15.7, which is a huge increase compared with the completion of sixth chemotherapy result.

What caused such a huge bounce in SUV value, while the SUV keep decreasing before the sixth chemotherapy?

What should my father do for future treatment?

Thank you so much!
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replied May 24th, 2010
In general, rising SUV values on CT-PET scans suggest either active tumor or (less likely) infection. A referral to a Radiation Oncologist could be considered at this time.

Sincerely/ Robert A. Wascher, MD, FACS

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