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Nerve pain and muscle spasms all over - What's wrong with me?

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Over the past 16 months the patient has experienced a range of neuromuscular symptoms and injuries across the body. Nerve pain has occurred in all four limbs, more significant in the left leg and arm. Muscular spasms have occurred in the left calf, left hamstring, left quad, right foot, lumbar back and the neck. Certain injuries or symptoms have resolved, while many remain ongoing. The majority of the symptoms have begun without a clear cause other than too much activity. MRI testing of the head, neck and spine have been unrevealing. Blood tests have been unrevealing. EMG of the left leg has demonstrated nerve damage. The patient’s functional limitations average around 5000 steps per day, with a maximum walking or standing endurance of 15-20 minutes, and overall arm use/movement at approximately 30% of normal. Pain levels fluctuate largely from 2-7/10 depending on activity. Physiotherapy has helped the patient regain some function and reduce some pain, but not addressed the overarching problem. Mental health symptoms include significant anxiety, mild depression and difficulty sleeping. At this time the doctors, including a general practitioner, a rheumatologist and a neurologist, are unsure of a diagnosis, prognosis or treatment plan moving forward. Neurontin has not had any positive effect.
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replied August 5th, 2019
Thank you for asking at Ehealth forum!

I read your question and I understand your concern.
Severe depression and early motor neuron disease are possible differentials. A trial of antidepressant and psychotherapy can be tried.
I hope it helps. Stay in touch with your healthcare provider for further guidance as our answers are just for education and counselling purposes and cannot be an alternative to actual visit to a doctor.
Take care

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