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Mononucleosis and an enlarged spleen

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Hello, I was recently in the emergency room and they sent me home saying that I don't have mono, nothing is wrong with my blood work, or urine test, or chest xray, but my spleen is enlarged, I need to know what could be wrong then? I'm confused to why my spleen is enlarged but they had no reason for it.


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replied April 23rd, 2010
Spleen Answer A11430
Hi and welcome to the forum! I am glad that I can help you.

You want to know why the spleen is enlarged during mononucleosis.

Mononucleosis (also known as mono) is a viral infection caused by the Epstein-Barr virus. This virus is transmitted through the saliva. It affects the immune system by weakening it. It is characterized with the following symptoms: fatigue, fever, headache, loss of appetite, night sweats, skin rash, soft, swollen spleen, sore throat, swollen lymph nodes, tonsilitis and weakness. The main place in the human body where the white cells are destroyed in conditions with or without infection is the spleen. The spleen is sensitive to touch and may easily rupture during exercise or palpation.

According to the data that you described, you may be experiencing mono. You may need to take antibiotics for treatment of the additional secondary bacterial infections. There is no antiviral treatment for mononucleosis. Because individuals experience hepatitis and enlarged AST and ALT liver enzymes, they should take medications that favor the regeneration of the liver tissue. Consider avoiding any exercise or any other contact within a month from the diagnosis of mono ( a home quarantine) to prevent yourself from complications and additional bacterial infections.

Please keep in mind that I provide medical information only. I am not able to diagnose medical conditions online. Please contact your doctor for further advice and information about diagnosis and treatment options.



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