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Metformin while trying to get pregnant ?

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i'm trying to get pregnant but is it ok to continue drinking metformin since i have PCOS.
please advice.

thanks
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replied November 4th, 2010
Welcome to the forum. I am really glad to help you out. Metformin is the drug of choice during for PCOS & thus women with PCOS often conceive while on metformin, and exposure during organogenesis (first trimester of pregnancy when the organ formation of the fetus takes place) is common.

At present, metformin is classified as Class B in pregnancy, with no evidence of animal or fetal toxicity. The animal studies have been done using metformin at more than double the dosage of humans without any effects on the growing fetus. Additionally, there are numerous reports using metformin for the treatment of gestational diabetes mellitus (GDM), without evidence of fetal harm. Although metformin does cross the placenta, a partial placental barrier likely exists, as maternal and fetal concentrations are different.

Overall, amongst the oral drugs, metformin is considered as safe during pregnancy. However, you should consult an endocrinologist/gynecologist for the



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replied December 11th, 2011
Hi Anand, thank you for the reply. I lost my first baby last January this year and was so sad that i didnt get back to writing lately.. now, i feel better and would like to start conceiving again.. thank you so much for your reply again.

May i ask if it is fine to start drinking milk for Mom though i'm still not pregnant?

Please advise. Thank you.
Regards,
Nesnie
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