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lymphoma & bone pain

I am diagnosed with non-Hodgkins Lymphoma, Stage IV. I had chemo in 2008 and got a remission. I relapsed in 2011. Have not had treatment again. Involvement identified by scans in abdomen, pelvis and chest. I have had pain in one leg, in the shin just below the knee for about a year. I have had X-raYS twice with no findings. The pain was very bad yesterday after non-weight bearing exercise. I do not run, but I do walk daily. How concerned should I be about the leg pain in relation to cancer involvement?
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