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Lupus symptoms- blood tests negative

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Hello. I am a 47-year-old female who has been having strange symptoms since turning 41. I was a healthy construction worker who never took time off and never needed to see a doctor. It seems like a proverbial punch in the face, I began getting symptoms I never had before: migraines, anemia, tremors, brain fog, vision problems, extreme joint arthritis, joint spurs, and the list goes on. I had time off, so I went to my doctor. Initial blood tests showed high ANA, but rheumatologists write it off. The last tests show negative for lupus, but now I have chronic kidney disease. I do not have diabetes, nor do I have high blood pressure. Is it possible for me to have lupus even though my blood tests are negative???
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replied April 8th, 2018
A positive ANA test is very sensitive for SLE/ Lupus. However, a more specific test like anti ds or anti sm antibodies would be required for confirmation. The symptoms you described fulfill the criteria of SLE but you didnt mention the investigations upon which the diagnosis was ruled out.


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