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Lump in throat and chest tightness

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I feel like I have a lump in my throat/neck and right chest tightness which usually appears or worsens after eating food. It feels like someone is pushing on the spot/indention where my neck meets my chest. I often feel winded and have a hard time talking or reading to my kids. It's always better in the morning and worsens throughout the day. It comes and goes throughout the day, and some days are better than others. I also have an undiagnosed condition which I am treating with Prednisone, but I'm not sure if all of this is related or not. My undiagnosed condition involves the above symptoms plus severe edema (esp. in face/eyelids and lower extremeties), itching/rashing on legs, hair shedding, bulging eyes. I've had lots of labs, scans, & a bone marrow biopsy. I have/have had low complement (C3, C4, CH50), low IgA, high eosinophils, low B12, and low iron stores (shown in BM biopsy). Any help you can offer would be wonderful. I do wonder if the throat/chest tightness could be anxiety?

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replied October 8th, 2009
Anxiety and Stress Answer A7482
Welcome to the forum!
The symptom you are facing of tightness of chest and throat and a lump in throat can be due to GERD or gastric reflux. This could be due to the effect of prednisone or due to your food habits or some drugs you took which increase the acidity.
The other possibility is that this unknown condition is also causing edema in throat. It could be allergy related too.
Malabsorption syndromes as seen in intestinal tuberculosis, HIV, tropical sprue, parasites in stool and Whipple’s Disease should be ruled out as a cause of low readings (low complement (C3, C4, CH50), low IgA, low B12, and low iron stores (shown in BM biopsy). Pernicious anemia, SLE or lupus (quite possible with rash and hair fall, high eosinophils), and other autoimmune disorders should be studied.
However without examining it is difficult to give a confirmed diagnosis and treatment on net. Hence consult your doctor and discuss these points. Hope this helps. Take care!

Specializing in facial injuries and pain, corrective jaw surgery, wisdom tooth removal, dental implants, bone grafting, and TMJ
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