Hello,

I've got some concerns and i'd like an opinion of my lab results. Thank you in advance.

The primary concern are my bilirubin levels and platlet count levels. Neither of them are too seriously high are low, but the are abnormal and I'm wondering if its an early sign of liver disease. My total bilirubin is 1.5 mg/dL and the lab says normal is less than 1.4. My platelet count is 145000/ul, where the normal minimum is 150,000.

Other results that are within normal tolerances.

AST 18
ALT 18
Alkaline Phosphatase 53
Albumin 4.7
Globulin 2.4
Total protein 7.1
eGFR > 60

So I'm confused because ASTs and ALTs low, but I've read an elevated bilirubin combined with a low platelet count could be a sign of concern.
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replied November 8th, 2017
Welcome to e health forum.

The presence of low platelets could be most commonly due to some form or viral infection, which in most cases would subside on its own and the patients would recover in due time.

If other parameters of blood investigations are abnormal, and patients symptoms are bothersome, then consultation with a doctor should be sought for proper help.

Bilirubin is an excretion product, and levels found in the body reflects the balance between ‎production and excretion. ‎

The normal range of Total serum bilirubin lies in the range of 0.1 - 1.2 mg/ Dl.

But in the determination of any liver conditions, just elevated bilirubin or liver enzymes levels are not significant.

The first sign of liver disease, that is Jaundice (Yellowish discoloration of the sclera of the eyes) due to accumulation of bilirubin, occurs with bilirubin range of 2-3 mg/d. Skin discoloration occurs at much higher levels.

Some general some symptoms of liver disease include nausea, vomiting, decreased appetite, ‎indigestion, change in stools, jaundice, itching, etc. ‎In severe conditions with greater liver dysfunction abdominal distension, swelling of the legs, ‎anorexia, lethargy could be evident. ‎

In case you have the above signs and symptoms, then additional tests including Urinalysis for bilirubinuria, Serum albumin, liver enzymes (ALT, AST, ALP, LDH), as well as a liver ultrasound - will be needed to evaluate the level of liver damage.

In case, if you do not have any other signs and symptoms other than the mild elevation of bilirubin levels, then these findings would be insignificant and you need not worry about them.

If you have any doubts or concerns consult your doctor or a hepatologist and seek a proper medical opinion.



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