Medical Questions > Nutrition > Nutrition Forum

Lack of Subcutaneous Fat Cells, no doctors who specialize...

Hi, Ive had this condition ever since I was young
and I would like to know if there is any specific
diet, hormone, or steroid which will cause a mass
gain in fat cell growth.

The old expression "can you pinch an inch" makes
me laugh, I can pinch 1/8 of an inch on my stomach,
and less on my arms and legs. I seem to have been
born with some form of lipodystrophy, but I am middle
aged now and it will probably kill me eventually if
I dont gain weight.

I realize I probably shouldnt complain, as everyone
else is trying to lose weight, but its a very serious
condition. I often find myself going into hypothermia,
teeth chattering and all at a mere 50degF temperature.

I have extremely strong muscles so I do not need to
gain any muscle weight at all.. just fat. I saw that
leptin was a possible treatment for this condition, but
there is currently no FDA approved treatment.

Should I go for the old quarterback recipe, of a dozen
eggs and a quart of cream with every meal? Ive tried
all the no-no's of weight gain, purposely mixing fats
and sugars in an attempt to get fat, nothing seems to
work. My skin is as thin as paper, and there are no
doctors who specialize in fat gain that I know of..

Ive been forced to resort to a high energy diet.. as
my body has 0 fat to get energy from. I would just like
to eat normal and be able to withstand low tempertaures
without going into shock

Any ideas? Rolling Eyes Thanks..
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replied January 17th, 2013
drugs that increase the recruitment of new, healthy fat cells may also help treat metabolic diseases. For example, peroxisome proliferator-activated receptor (PPAR) gamma agents are commonly used drugs to treat type 2 diabetes mellitus. Pioglitazone is an example of a PPAR gamma agonist drug that lowers blood sugar and improves lipid levels. As part of PPAR gamma drugs mechanism of action is increasing the amount of functional or healthy fat tissue.[18] As a result, many patients treated with these types of drugs increase body fat. Initially, it may seem odd and almost paradoxical to use a drug that increases fat tissue to treat metabolic diseases that are caused by too much fat tissue. However, when explained through the concept adiposopathy, no such paradox exists. Because PPAR gamma agents work by increasing the amount of healthy, functional fat, decreasing the proportion of sick abdominal fat tissue, and decrease fatty liver. All of these effects upon fat tissue are effective in treating sick fat and improving metabolic disease. Thus, it is within the framework of sick versus healthy fat, that the rationale behind the use of these drugs is easier to understand.
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