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is duphaston safe with history of miscarriage?

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is duphaston safe to use in wk5 of somebody that has a history of miscarriage and, or threatened abortion

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replied June 6th, 2011
First Trimester of Pregnancy Answer A23788
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Duphaston contains dydrogesterone, a synthetic hormone similar to the naturally occurring sex hormone in your body, progesterone. It is used in treatment for a wide range of menstrual disorders that are thought to result from a lack of progesterone in the body. As it helps regulate the healthy growth and normal shedding of the womb lining, it may be used in the treatment of menstrual disorders such as absent, irregular or painful menstrual periods, infertility, premenstrual syndrome and endometriosis. It may also be used to minimize the overgrowth of the womb lining (endometrium) due to estrogen (the main female sex hormone) in hormone replacement therapy (HRT) following menopause. By maintaining the womb lining, dydrogesterone is also useful in helping prevent miscarriage (spontaneous abortion) in women who have suffered repeated miscarriages or who may miscarry. There are no known harmful effects when this medicine is used during pregnancy. It can be used for management of abdominal pain and bleeding during pregnancy (threatened miscarriage) or history of miscarriages (habitual abortion).
However if your doctor has not prescribed it or if you are pregnant, you should consider discussing about its use with your gynecologist. Be in regular follow-up with your treating gynecologist/obstetrician.
Take care.

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