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I am noticing an acute onset of hypertensive symptoms after even small doses of 25-50 mg of Sertraline. My blood pressure went up to 161/93 94 just with 50 mg at once. I do take Focalin 40 mg, but I notice the hypertensive and tachycardia events when I take Sertraline in the evenings after Focalin doses during the day. My only theory is that Sertraline may be inducing a cortisol increase resulting in increased BP and Pulse Rate.

Here's an example:

Androgel 40.5 g
Focalin 10 mg

Focalin 10 mg

Focalin 10 mg


Focalin 10 mg
Propranolol Tablets 40 mg
Sertraline 50 mg (This is when the hypertension and tachycardia will begin)

Sertraline 75 mg
Melatonin Complex Herbal Supplement

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replied March 10th, 2019
High Blood Pressure and Hypertension Answer A64861
Thank you for asking at Ehealth forum!

I read your question and I understand your concern.
This high BP is due to your underlying psychiatric disorders. You need to adjust your propanolol dose.
I hope it helps. Stay in touch with your healthcare provider for further guidance as our answers are just for education and counselling purposes and cannot be an alternative to actual visit to a doctor.
Take care

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