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A question I have is about stimulants and the HPA axis. Does taking stimulants for ADHD like Dexedrine and Focalin likely to suppress the HPA axis in individuals using those medications long-term or greater than 6 months?

I am concerned my LSH and FH deficiencies may not be primary hypogonadism as my endocrinologist believes because of what I know from the pituitary gland being suppressed or inhibited by specific medications.

Additionally, I am also on synthetic testosterone for primary hypogonadism and have been diagnosed with primary central idiopathic hypogonadism two times by my primary care practitioner as well as my endo doctor.

I would like to make sure my HPA axis functioning is adequate as with the long-term use of stimulants for ADHD at high doses with Androgel applications for my low testosterone levels, I am having concerns over developing issues in the future.

FSH and LH were low after 4.5 months with no Androgel, as were low the past 5 labs over 4 years.

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replied December 12th, 2018
Gland Disorders Answer A64655
Thank you for asking at Ehealth forum!

I read your question and i understand your concern. ADHD meds wont affect your HPA axis. Your primary hypogonadism diagnosed by your endo is not attributed to these meds.

I hope it helps. Stay in touch with your healthcare provider for further guidance as our answers are just for education and counselling purposes and cannot be an alternative to actual visit to a doctor.
Take care

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