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Feeling fatigue with mononucleosis

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after seeing 3 doctors, i was diagnosed with mono in sept 2008. by then the test showed i was in the convalescent phase. i had a swollen gland in the back of my neck that june. the fatigue started then headaches, etc but what was really disturbing was the night time convulsive type jerks. this is when the mono entered my nervous system causing vaginal/rectal spasms and pain, twitches from head to toe, tingling etc. anyway to make a very long story short, i started feeling better a few months out but it has been off and on. right now i am having fatigue days that are getting closer together and i am tired every day. this makes me down and emotional which is not like me. i think it may be time to revisit my neurologist who discovered the mono. i seem to be feeling worse these days. is this normal and do you think it will resolve with time? i am worried it may lead to something else.


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replied April 12th, 2010
Mononucleosis Answer A11220
Hi and welcome to the forum! I am glad that I can help you.

You want to know whether it is normal to feel fatigue when experiencing mononucleosis.

Mononucleosis (mono) is a contagious infective disease caused by the Epstein-Barr virus. The virus is transmitted through saliva. The virus affects the liver and the spleen and has a characteristic blood count (increased monocytes). It is characterized with the following symptoms fatigue, fever, headache, loss of appetite, night sweats, skin rash, soft and swollen spleen, sore throat, swollen lymph nodes in your neck and armpits, swollen tonsils and weakness. It may lead to the following complications: jaundice, enlargement of the spleen, and even rarer complications such as encephalitis (brain inflammation).

Given the data that you described, you may have experienced the twitches and the tingling sensations due to increased body temperature. Certain individuals respond to increased body temperature with seizure-like twitches of the muscles. You may consider seeing neurologist to rule out or to confirm encephalitis or seizure-like changes. The recovery from mono may take several weeks due to lesion of the liver during which individuals may experience fatigue. You may consider taking antibiotics if you experience additional (secondary) bacterial infection.

Please keep in mind that I provide medical information only. I am not able to diagnose medical conditions online. Please contact your doctor for further advice and information about diagnosis and treatment options.

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