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My husband has elevated liver enzymes and a positive ANA what could this mean? We are scheduled for a biopsy next week but I am worried. He was recently diagnosed with fatty liver disease but when his ANA came out positive they said it could be PBC. He is 26 years old. Any advice would help us out!

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replied December 5th, 2015
Liver Disorders, Hepatitis A,B,C Answer A55109
Welcome to e health forum.

Abnormal liver functions (raised enzymes) and Positive Anti Antinuclear antibodies (ANAs) would be indicative of Primary Biliary Cirrhosis.

PBC is a chronic form of liver disease as a result of autoimmune causes, which causes progressive liver damage and finally end stage liver disease.

The management of the condition is mainly directed to slow the disease progression and relieve the symptoms. Liver transplantation may be done as a life saving procedure.

It would be recommended that you consult a hepatologist and seek a proper medical opinion.

I hope this helps.

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