My wife had two miscarriages (fetus dies at 8-9wks). After second m/c we did all tests related to blood coagulation, and it all turned out normal. Also no family history of miscarriages or thrombosis. She is now 6wks pregnant and has been on folic acid 5mg and baby asprin since conception. After an ultra scan her doctor advised that she should start taking Duphaston 10mg three times per day. Would be grateful if you can guide us whether this prescription is approprate and safe for her and the baby.
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replied June 21st, 2014
Welcome to ehealthforum,
If she is having recurrent miscarriages around the same time, then there are chances of problems like luteal phase defect, hormonal insufficiency etc. If worried, and if pregnancy has been confirmed, consider getting serial HCG levels checked to see if the levels are rising adequately/doubling up within 48-72 hours confirming that pregnancy is going smoothly. If HCG levels are not adequate, then external hormonal supplements (like Duphaston and progesterone) would be considered to be started to help her in preventing miscarriage. If HCG levels are rising, repeat ultrasound scan done after 2 weeks will also help to confirm the gestational age and pregnancy viability. She should visit her doctor/gynecologist at the earliest for further evaluation and assistance. She should be in regular monitoring and follow-up with her treating doctor/gynecologist and report any new/abnormal symptoms immediately. She should take adequate rest. She should drink plenty of water. She should maintain healthy diet. She should look out for danger signs like increase in intensity of abdominal cramps, increasing back pain, fresh bleeding etc. She should avoid bending or lifting any heavy weights and avoid heavy work. She should avoid standing for long duration and avoid climbing stairs. She should avoid use of caffeinated and carbonated beverages.
Take care.

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