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does rising TgAb and sreum ferritin indicate recurrence?

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Had TT 2007 Dx Hashimoto disease. Hurthle cell adenoma >4cms.Multinodule goitre. No RAI given after TT. T4 dosing hyper on low doses and hypo on higher doses, with severe FT4 and TSH lowering after several months.150mcg thyroxine now. TgAB increased to 99 recently from 83 1 yr ago, 63 previous year. TPO ab's now 160 dropped from 180 in 2011, in 2010 190. Serum ferritn raised from normally 40 for many years to 287 in March 2012. Low normal iron studies. Potassium slightly decreased, kidney function testing showing some lowering function. L kidney 9.2 cms R kidney 11.5 cms with increase since 2010 (both normal at around 9cms at that time) Q; does the rising of TgAb and sudden sreum ferritin indicate a recurrence of any thyroid cancer? U/S shows no tissue in thyroid bed. Docs refusing to do further investigation.Am aware TPO can take up to 6+ years to dissipate and less for TgAB, however mine have increased slightly. (should be less than 60U/ml)Thank you.


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replied May 1st, 2012
Thyroid Cancer Answer A34514
Hi,
Welcome to the ehealthforum and I am really glad to help you out.

Thyroglobulin levels should be undetectable or very low after the surgical removal of the thyroid (thyroidectomy)or after subsequent radioactive iodine treatments. If levels are still detectable, there may be normal or cancerous thyroid tissue remaining in the person's body, indicating the need for additional treatment.

Based on the results of your thyroglobulin test, your doctor may follow up with a radioactive iodine scan or radioactive iodine treatments to identify and destroy any remaining normal thyroid tissue or thyroid cancer. You should discuss this with your doctor.

I sincerely hope this information helps. Take care.


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