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Depression and ADHD medications

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I'm experiencing chronic dysthmia with ADHD stimulant use as well as problems with my ability to maintain focus even on high dose methylphenidates and amphetamines. I am on Focalin 40-50 mg a day and at that dose range I am experiencing significant depressive episodes in the evenings after I've taken all the doses divided in the day as four doses 10 mg each (Focalin).

I am feeling as though my depression is MORE bothersome than the ADHD symptoms are, but I also know that one of the symptoms of depression is difficulty maintaining focus and having interest in certain life's activities.

I don't know whether or not it is helpful to keep taking stimulants for ADHD knowingly that will make me more depressed later in the day, but yet I also want to get tasks done and pay attention in important lectures and with homework assignments.

I sense a need for a balance between depression+ADHD, but in order to be on SNRI med like Pristiq or Effexor which I like, I can't tolerate Focalin.

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replied March 10th, 2019
Depression Answer A64860
Thank you for asking at Ehealth forum!

I read your question and I understand your concern.
Avoid antidepressant like effexor because there is high risk of serotonin syndrome. You can take bupropion.
I hope it helps. Stay in touch with your healthcare provider for further guidance as our answers are just for education and counselling purposes and cannot be an alternative to actual visit to a doctor.
Take care

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