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Would it be a reasonable concern to bring up with my psychiatrist in a few days that I believe that the Zoloft/Dexedrine combo of medication I am on would be contributing to my fatigue symptoms because of the zoloft decreasing norepinephrine and dopamine as well as the high dose Dexedrine decreasing my natural ability to produce those two catecholamines?

I feel better with energy off psychotropic medications, yet I notice my mood seems to get worse with them so balancing these two particular areas of my health have been more frustrating than I can possibly convey to you.

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replied August 28th, 2018
Chronic Fatigue Syndrome Answer A64326
Welcome to e health forum.

Yes, it is possible that combination of psychiatric medications can have various side effects and hence you should speak to your treating psychiatrist who can help you in this regard.

Either a dose adjustment or a change of those medications can help in helping your symptoms and make you feel better.

I hope this helps.

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