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Cayenne pepper& prostate cancer

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In April 2006 I was diagnosed with prostate cancer after a biopsy - Gleason score 6(3+3). I was strongly urged to have the prostate removed immediately. I refused & starting doing research. I found a Cedars-Sinai Medical Center/UCLA School of Medicine study that said that capsaicin (the stuff that makes pepper hot) fed to rats bred to have human prostate cancer had caused the cancer cells to commit suicide!

I immediately started taking cayenne pepper capsules daily. I took the equivalent human dose from the study & made that my goal. I gradually consumed more each week until I reached what I thought was the right dose. I had improved symptoms within the first two weeks - urination was easier - I had not been able to reach orgasm at the time of diagnosis but that too improved & is still improving.

Last month I decided to see a urologist to see what was involved in "Watchful Waiting" - he wanted to do another biopsy since it had been two years - I agreed & the results came back clean - they found no cancer - not a trace! My doctor was stunned & said that in 18 years he had never seen such a result. We had it double checked & I am indeed cancer free.

I am confident it was the cayenne that made the tumor disappear - given the study results.

I plan to keep taking it indefinitely & I recommend it to any male who has been diagnosed with either BPH or prostate cancer.

I am not selling anything - I believe cayenne pepper from any source would perform the same.

I can provide links to the study I mentioned & to recaps of it but you can find it by searching for cayenne + prostate cancer.
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First Helper PepperLover

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replied March 18th, 2008
Extremely eHealthy
very interesting
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replied November 18th, 2008
hi pepperlover
i was just diagnosed and would like to check out the link to the study you describe.
can you give me link?
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replied February 21st, 2011
cayenne and prostate cancer
cayenne suppliments contain less than 1% capsaisan. the study translates to 400mg capsaisan 3x per week for a 200 lb male. That translates to 40 grams of cayenne x3 at the minimum.
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replied June 10th, 2011
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Hot Peppers Make Prostate Cancer Cells Die
(NaturalNews) Hot peppers are great for spicing up food. They may be even better for keeping the human body feeling in the spice of life. Capsaicin is the active ingredient in hot peppers and the one that turns up the heat. It is a compound useful in nature for preventing pepper plants from being eaten by insects and animals. When capsaicin is consumed by humans in the form of hot sauce, chili peppers or cayenne pepper, it offers a wealth of health benefits. One that has received much recent attention is the ability of capsaicin to make prostate cancer cells commit suicide.

Moderate dose of capsaicin makes 80 percent of prostate cancer cells die

In 2006, a team of researchers from the Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai Medical Center, found that capsaicin induced 80 percent of human prostate cancer cells growing in mice to follow pathways leading to certain death. They also found that prostate cancer tumors in mice fed with capsaicin were about one-fifth the size of tumors in non-treated mice. Additionally, capsaicin had a profound anti-proliferative effect on cultured human cancer cells according to a scientist at the UCLA School of Medicine. It dramatically slowed the development of prostate tumors formed by cells from the same lines as those grown for the mouse models.

The scientists estimated that the dose of pepper extract fed to the mice was equivalent to giving 400 milligrams of capsaicin three times a week to a 200 pound man. This would be about the amount found in three to eight fresh habanero peppers, depending on how hot the peppers were. The hotter the pepper, the greater the capsaicin content. Habanero peppers, which are native to the Yucatan, have the highest amount of capsaicin. On the Scoville Heat Index, habaneros score 300,000 heat units. Jalapeno peppers, popular in the U.S., score between 2,500 and 3,000 heat units.

In 2008, these results were corroborated by researchers in Madrid, Spain who identified ten genes that were down-regulated and five genes that were up-regulated upon capsaicin treatment in human prostate cancer cells. They found that blocking the action of one of the up-regulated genes significantly reduced capsaicin-induced cell death. From these findings they concluded that the mechanism by which capsaicin causes prostate cancer cells to die had been identified.

In those prostate cancer cells that depended on the predominant male sex hormone, testosterone, for their growth, capsaicin reduced cell proliferation in a dose-dependent manner. Prostate cancer cells that were not dependent on testosterone for their growth responded to capsaicin in a similar manner.

Capsaicin reduced cancer cell production of prostate specific antigen (PSA), a protein that is a marker for the presence of prostate cancer. Production of PSA is regulated by male sex hormones.

Capsaicin is effective against other types of cancer

Research from India recently investigated the effect of capsaicin on fat metabolism during induced lung cancer in mice showing abnormal changes in tissue and serum lipids, lipoproteins, and lipid metabolizing enzymes. Treatment of 10 mg per kg of body weight showed an ability to reduce all of these alterations and restore normality that they described as "remarkable". (Archives of Pharmacal Research, February).

In another study investigating how oxidative stress mediated lung cancer, lysomal damage was found to be an indispensable event in the development of some lung cancers. Capsaicin was able to completely prevent lysomal damage, and was effective against induced lung cancer. (Fundamental Clinical Pharmacology, February).

Scientists investing the effects of capsaicin against human breast cancer noted that the compound has been shown to exert powerful biological activity including anticarginogenic, antimutagenic and chemoprotective effects against many cancer cell lines. When they tested it against a highly malignant breast cell line, they found that treatment with capsaicin for 24 hours resulted in dose-dependent death of the cancerous cells. (Oncology Report, March).

A recent study investigating capsaicin on highly metastatic melanoma cells found its anti-mutagenic activity inhibited the migration of melanoma cells at low doses without showing obvious cytotoxicity. The scientists concluded that capsaicin administration should be considered an effective approach for the suppression of invasion and metastasis in malignant melanoma. (Experimental and Molecular Medicine, October, 2008).

In an earlier study at M.D Anderson Cancer Center in Houston, researchers tested capsaicin on human skin cancer cells to analyze how the cells would react. They found that the majority of skin cancer cells exposed to the substance died. Capsaicin seemed to kill cancerous cells by damaging their membranes and limiting the amount of oxygen that could reach them. Drug companies have long searched for a drug that could do just that. Any compound that could limit oxygen in targeted cells would be highly effective against many forms of cancer.

High intake of capsaicin correlates with lower death rates from cancer

In countries where high intake of capsaicin is the dietary norm, cancer death rates for men and women are significantly lower than they are in countries with less chili pepper consumption according to statistics from the World Health Organization. Experiments have shown that capsaicin seems to be able to detoxify a wide range of chemical carcinogens which, if left to roam the body, could create mutations leading to full blown cancers.

Learn more: http://www.naturalnews (dot) com/026076_PSA_capsaicin_cancer.html#ixzz1 Ot8IrMJi
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replied July 24th, 2013
A biopsy may come back negative, meaning the cell tissue that was extracted showed no cancer. That does not mean you are cancer-free. I'm surprised your urologist did not point that out to you. Also, what do you mean by "We had it double checked"? Did you have another biopsy? or did you and your doctor just look at the lab results report again?
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