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four years ago I suddenly got a case of severe hives last lasted eight weeks. Oral steroids, steroid injection, and antihistamines could not control the rash. I had Allergy testing done and up negative for allergies. It was also noted that I had a goiter but thyroid blood work came back normal. After the eight weeks the hives suddenly stopped and my doctors passed it off as a freak thing with no explanation. Since then I have had more random allergic type reactions, hives, other rashes, eye swelling shut randomly, tongue swelling.
It has recently gotten worse with my tongue swelling daily. Not to the point that I can’t breath but to the point that it is uncomfortable and my tongue is “scalloped”. After four years of these reactions I tried again to find the cause and spoke to my doctor about my concerns. She ran a CBC, TSH, t4, t3, Hepatic Panel, checked vitamin D and B12 levels, and it all came back normal but I’m still having reactions. Any advice on what to do from here?

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replied January 29th, 2019
Allergies Answer A64766
Thank you for asking at Ehealth forum!

I read your question and I understand your concern.
I would suggest you to have C1 esterase inhibitor level to rule out hereditary angioedema. Take antihelminthic if you are living in endemic area.
I hope it helps. Stay in touch with your healthcare provider for further guidance as our answers are just for education and counselling purposes and cannot be an alternative to actual visit to a doctor.
Take care

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