Hello and welcome to e health forum.
The twitches that you have described could be a indicator of benign fasciculations, which can occur even in most normal individuals.
Unless, they are very severe and cause much functional problems, treatment is not needed.
Such conditions actually do not need amputation of toes.
The condition that you are worried about, which may need amputation is diabetic neuropathy induced gangrene of the foot. But this will occur only with foot related injuries.
You might consult with your treating doctor who can examine you and counsel you accordingly.