of course, i don't know very much in addition to not being very smart, but i think the concern is that taking megadoses of C might cause your uric acid level to drop more thus sparking an attack. however, as much as 1000 mg's will lower it slightly. how much? not sure. i take 1000 mgs a day and drink two tblsp of cherry juice concentrate a day. both are said to lower ua levels. who knows?

Thank you!

The reason that vitamin C can be helpful in avoiding gout flares is that it counteracts the effect that ingesting fructose has on the liver, which results in its production of excess uric acid. Fructose is a natural sugar which is a significant component of every sweetener termed natural. Fructose is the main sugar in fruit, but when you eat fruit you get it with vitamin C. You can learn more from Dr. Richard Johnson's book "The Sugar Fix: The High-Fructose Fallout That Is Making You Fat And Sick". Dr. Johnson is chief of nephrology at U Fla, Gainesville, He is regarded as one of the world's foremost experts on uric acid.