Since Vitamin A is stored in the liver, harmful effects can build up gradually. However it is extremely unlikely that any problems would occur unless you are taking 50,000 IU or more a day. Even at teh 50,000 unit level, you would have to continue that dose every day for months to reach a possible toxic level.Some people can tolerate more. 10,000 to 25,000 IU a day should have no problems at all. Serious side effects of vitamin A can be prevented by heading early warning signs. These include fatigue, abdominal discomfort, bone and joint pain, throbbing headache, insomnia, restlessness, sweating, hair loss, brittle nails, constipation, menstrual irregularities and swelling of the ankles.
FYI - Large amounts of carotene may cause your skin to turn orange. This is not a toxic side effect and will go away as carotene is stopped.