Did anyone ever tell you that you had Anklosing Spondolyitis? I'm sure they would have of tested you for the gene marker HLAB27. If you do have this condition TNF blockers help somewhat. Thet are Remicade, Humaria, and Enbrel. My husband suffers every day with this and he has been on remicade for about 5 years. Maybe you can inquire good luck ... more