I never spotted on brand-name Seasonale, never spotted on Quasense, but am spotting like mad on Jolessa. I am finishing the 6th week and I've been spotting for the last 3. I looked back at my diet, any supplements (multivites, Caltrate almost every day, no herbal supplements), & medications (occasional NSAIDs, Wellbutrin XL 300 mg) and found no... more