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Undifferentialted (high-grade) endometrial stromal sarcoma

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April 2nd, 2012
I had a hystorectomy on February 17, 2012, due to a tumer found in my cervix.

This is my final diagnosis:
Undifferentialted (high-grade) endometrial stromal sarcoma
Tumor measures 4.5 cm in maximal dimention
tumor extends to within 1 mm of inked soft tissue margins
Foci suspiciaous for lymphvascular space invasion
inactive endomtrium
Surgery was done on March 23rd, Dr. Marcia Bowling, oncology and she removed 12 lymphnodes and did a pelvic wash - The overies, the lymphnodes and the pelvic was all came back negative for cancer cells.

Pet Scan done on March 16th came back negative for cancer - full body
Do you recomend this additional treatment?
radiation - 6 weeks of radiation 5 days a week for 6 weeks.,
4 days of Chemo, every 21-28 days for 4 months using the drugs Ifosfamide and adriamycin/doxorubicin.


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replied April 5th, 2012
Cervical Cancer and Ovarian Cancer Answer A33584
Welcome to e health forum.

In case of endometrial Sarcomas of high grade, chances of malignant cells being spread across the pelvic cavity is definitely possible. Hence such cells need to be killed by proper means.

Surgical excision can help to clear the malignant tumors which are visible to the eye (macroscopically or by microscopic analysis of the additional tissues removed along with the tumor tissue). But it cannot eliminate the malignant cells which have spread into unremoved tissues. In this scenario chemotherapy and radiotherapy comes into play. These adjuvant treatment modalities help to kill the remaining cells that cannot be completely removed.

Hence it is highly recommended for you to follow up with your treating doctors and continue with the proposed line of management.


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