will shrooms effect my mood or is there a possibility of it doing so? I had a few drinks last night and this morning i'm in a shitty mood. the past few weeks of my treatment, i've been getting a lot better and today i've just bottomed out. I'm not drinking any more until I am at a therapeutic does and my doctor says that in moderation, drinking is fine. I was wondering if "shrooms" or psychedelic mushrooms would cause a similar or more negative effect.