Anxiety can certainly cause what you are experiencing, tripmum2, so failing something showing up in the tests you've had, it may well be the culprit, especially as you have major stressors in your life.

I'm curious about the ondesetron. Bristol-Myers Squibb initially developed this as an anti anxiety medication back in the late 1980s, but then decided to focus on its anti nausea properties as a counter to what is the most common side effect of chemo and radiation therapy. I'm assuming that you only took it for a short time because its too expensive to use as an antidepressant (its a SSRI variant) and I can't see the PBS paying for what is an off-label use.

Gastro intestinal disorders such as Gastroesophageal Reflux Disease (GERD) and Irritable Bowel Syndrome (IBS) often co occur with anxiety disorders. The vagus nerve directly connects the gut to brain regions involved in anxiety (and depression). In fact vagus nerve stimulators are now being successfully used to treat depression that doesn't respond to drugs or psychotherapy.

Best wishes, mate.

I am assuming that you are at the end of your rope, the nausea you experienced in the past as crippling. You were dreading it returning and it did. Now you are possible stuck in a loop, your dread of the nausea causes you to become anxious, which in turn causes the body to react, sending the nerve stimulation through the body, causing nausea. I am dealing with something similiar, and am now on clonanzapam until I can get to a psychiatrist. I saw a psychologist yesterday, and when I told her I was taking .5 mg a day, she told me to go back to my GP and get an increase, and to use the meds as I needed. Today I took 1 mg and all the symptoms subsided. Some minor nausea but NOTHING as bad as it was. Please get with a phychiatrist and see what he thinks. It could be all in your head and still VERY VERY REAL!

Thanks to those who replied to my question - Since I posted my message My GP put me on maxolon and xanax (Kalma), the results were amazing I was feeling better within a few hours and thought I was better for two weeks then this last weeks the symptoms have returned almost as bad as befroe as despite the Xanax which is supposed to calm anxiety< I feel more anxious than ever. Any ideas please

I know this is an old post but I figured I'd reply anyway! I'm a young male and I have had pretty much identical sympthoms for the past 4 years, I get sereve bouts of nausea about 4/5 times a year which last 48hrs to a week, during which time I often can barely hold down water and since I have weight issues (being underweight) it can become quite serious... which adds to the stress! I have also suffered less severe nausea (but still uncomfortable and appetite inhibiting) on a regular basis. I have always had an interest in medicine and have been to every specialist/alternative form of medical consult available. I have a keen interest and background in psychology, which is actually intrinsic to my problem (over analytical.... not helpful with stress) and so based on all that this is my opinion on your problem! Drugs definitely don't help, I'd have no problem 'popping' anything to ease the pain (I take protium for my GERD) but anxiety pills don't relieve the underlying problem so they will eventually reoccur!

It was hard for me to come to terms with the idea that my problem was mainly psychological (although these sympthoms nearly always go hand in hand with gastritis/gastroenteritis and the general inflammatory reactions that can occur from these) but it my opinion it is very much due to concious and subconcious stress or moreover the inability to deal with these!

Psychological help, acupuncture and naturally keeping your life as stress free as possible are helpful tools to ease the condition but personally I feel a more fundamental change in outlook toward lufe is needed. I have never attended a yoga class and I don't know any of the classic yoga poses but over a year ago I was given a book which discussed yoga in a traditional sense (theory) outlining 10 principles to living your life, the more I reread these and casually researched them, the more I relaxed and the less often/severe the sympthoms occured! It's basically a taoist/buddhist philosophy of life but it doesn't have to be a huge part of your life or affect your religion if you are religious!

In essence I would highly recommend studying these principles, the importance of breath(breathing) in your life and in your body. Maybe attend some relevent classes (again most local yoga class will be more about stretching and although there prob will be a dialogue about breathing and meaning it'l most likely be too superficial to be particularly benefical for your purposes). As someone said in previous reply... it can be mainly in your head and still very much real, no medical person in the world would deny the implicit connection between body and mind! I honestly feel your pain, it is a horrific debilitating condition! I hope this helps.

I know this is a long reply and to be honest I feel like saying alot more (particularly on the cause of condition) so if you've anyone has any other questions. . . . =)