I was on zyprexa when I strted having severe muscle spasms, lasting 1.5 hours two days in a row. I had just gone suddenly off my meds for three days. This was in March 2006. In May I was taken off zyprexa. Now Im on clozaril and have daily muscle spasms. Ive had an MRI-- it didnt show anything. I also have a history of years of taking risperdal--from 16 to24, Im now 29.