Yes, Vitamins can most definately make you tired, that do that to me also, and many other people as well. I've tried different vitamins, including the Mega vitamins, and they make me very tired. I am going to stop taking vitamins for a while, to see how I feel, and just eat better. You can get vitamins thru fortified foods, such as cereals, oatmeal, etc....and also fruits and veggies as well. I think maybe vitamins cause an im-balance in our delicate system.
I don't eat any processed foods.
Try not taking them for a while to see how you feel. I mean, if you feel worse, more tired taking them, that's telling you something.