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What Causes Neutropenia And Lymphopenia?

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Leukemia<br />
question: ive had neutropenia and lymphopenia for 2 years and after many many blood tests to rule out countless diseases its still not known why.My last 2 tests have said my neutrphils show left shift and to repeat in 2 weeks as "sl is lower than last".I dont know what either of these things mean.Ive read that neutropenia is closely linked to some leukemias and what I would like to know is could this be changing to leukemia?These are my last blood reaults..

(mn)repeat in 2 weeks,sl lower than last
hb..12
wbcs/..1.96
platelet..191
neutrophils..0.37
lymphocyte..1.05
basophils..0.01

also I get really bad back pain and my knees gat really painful.I get really hot at night and I get really breathless.I know that im not aneamic so I dont know if any of this is relevent.If im at a risk of leukemia id rather know than drive myself silly with worry needlessly.Id really appreiate your opinion.

Mandy<br>
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replied February 6th, 2007
Leukemia Answer A2285
The most significant laboratory signs of leukemia are an increased number of leucocytes (leucocytosis) and the existence of pathologic (malignant) forms of white blood cells. During leukemia, the number of erythrocytes and thrombocytes in the blood decreases. A differential blood count will indicate which population of white blood cells has increased and if there are pathologic (malignant) forms of blood cells. Lleucocytosis is alsp present during many other infective diseases, but pathologic forms of white blood cells are only present in the blood during leukemia. Acute leukemia can cause neutropenia and lymphopenia when the pathologic forms of leukocytes become dominant over the normal white blood cells. Severe recurrent infections, bleeding and signs of anemia are typical for acute leukemia.
Reasons for neutropenia and lymphopenia are various. Every possible explanation should be explored to identify the cause of neutropenia in your body.
1. Infections: viral (measles) and bacterial (tuberculosis, abdominal typhus, brucellosis, ricketiosis…);
2. Medications;
3. Radioactive irradiation;
4. Hematological diseases: megaloblastic anemia, acute leukemia, mielodisplasia, aplastic anemia, multiple myeloma...;
5. Autoimmune diseases: lupus, Felty-syndrome, primary neutropenia, cyclic neutropenia..., and
6. Idiopathic chronic neutropenia.


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