Diabetes Mellitus Type 1 Triggers; DM-1

Immunization against the Hepatitis B-virus can not provoke diabetes mellitus type 1. Diabetes mellitus type 1 (DM-1) is considered an autoimmune disease. Beta-cells produce insulin. Insulin is a hormone that has crucial importance in the metabolism of the carbohydrates. Specifically, during diabetes, the beta-cells in the "Langerhans’s islands" of the pancreas create insulin. The immune system creates antibodies and cytotoxic T-lymphocytes against the beta cells. Th precise etiology of autoimmune diseases like Diabetes mellitus type 1 remains unknown. It is assumed that microbes (bacteria and viruses) trigger some types of autoimmune diseases but there aren’t strong evidence that confirm the theory. In the case of diabetes mellitus type 1, the assumed viruses include: parotitis-virus, cytomegalovirus, rubella-virus and coxaci-virus. These viral infections are very common in the normal population, but DM-1 is a very rare disease. This fact leads us to the conclusion that the viruses can cause DM-1 only in people who have a defect in their immune system. In other words, people diagnosed with DM-1 have immune systems that are genetically predisposed to fight against its own beta-cells in the pancreas. Your family data tells me that in your family (mother) there is a predisposition for developing autoimmune diseases (scleroderma).



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