Rupture of the gallbladder is fatal condition without surgical intervention. The gallbladder usually ruptures due to severe infection of its wall or because of tumor. After the rupture, all the contents of the gallbladder (bile and bacteria) spill into the peritoneal cavity causing acute diffuse inflammation (peritonitis). Acute diffuse peritonitis is a serious condition because an infection can be easily spread to the whole body, causing sepsis and septic shock. Surgical intervention saves a patient’s life if it is done on time. A prognosis also depends upon the presence of additional or previous diseases.