Does anybody no the difference between
secondary and primary parkinson's disease.
I know that secondary pd is when there is
a known source that caused it but are they
still the same thing just one with a cause
and the other with the cause unknown?
In both primary and secondary Parkinson,
dopaminergic neurons located in the
substantia nigra of the corpus striatum
are destroyed so there the same symptoms
are present.
In primary Parkinson (Parkinson disease)
the reason for progressive dying of those
neurons is unknown. One of the possible
hypothesis is that those neurons normally
dies with aging but some people are born
with less dopaminergic neurons in the
substantia nigra so when they become older
they are missing those neurons more than
the rest of the normal people.
In secondary Parkinson (Parkinson
syndrome) dopaminergic neurons in the
substantia nigra can be destroyed by
various known reasons like brain
infection, cerebro-vascular insult
(stroke), cerebral atherosclerosis, brain
trauma, poisoning with heavy metals or
pesticides etc. Beside Parkinson symptoms
there can be also present some other
symptoms typical for the primary disorder.
For example, high temperature in brain
infection.
