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Womens Health > Birth Control Forum > Blood Clots and Protein Deficiencies
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Q: Blood Clots and Protein Deficiencies
asked by: DoctorQuestion on September 22nd, 2006
I would like to know what the name for the condition that cause u to have blood clots and a protein defficiency in the blood. I have just developed this in the last month and a half and never had any problems with this in my life.


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Dr. Nikola Gjuzelov , MD
replied on October 5th, 2006
Birth Control Answer A1569
It is impossible to give you a precise answer without specific blood laboratory analyses.
Protein deficiency in the blood could be total, or perhaps only some blood protein fractions are decreased. Blood protein fractions are albumins, globulins and fibrinogen.
Albumins are produced in the liver. Their level is decreased in cases of starving, large skin burns, some liver diseases, and in cases of kidney failure when the albumins are lost through the urine, etc.
Globulins have 3 fractions: alpha, beta and gamma. Alpha and beta globulins are produced in the liver and they are decreased in the case of liver failure. Gamma globulins are antibodies and they are produced by the immune system. They are decreased in cases of immune deficit.
Fibrinogen is produced in the liver. Its blood level decreases in cases of smaller production (liver failure) or higher spending (increased blood coagulation).
A blood clot develops due to 3 factors: damage to the blood vessels wall, blood circulation stasis, and hyper-coagulation conditions. The first 2 factors are responsible for forming local blood clots while the third factor (hyper-coagulation) has a general influence. Coagulation depends upon both coagulant and anti-coagulant factors. In normal occasions, anti-coagulant factors are dominant and the blood stays in liquid condition. Thrombocytes and the vascular endothelium (inner layer of the blood vessels) also have a very important role in blood coagulation. Most of the coagulation and anti-coagulation factors are produced in the liver while some are produced by the thrombocytes and vascular endothelium.



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