Ovulex is a natural product for stimulating ovulation. You may try it because it won’t harm you but shouldn’t expect any spectacular results. Poly cystic ovarian syndrome (PCOS) is a complex endocrine disorder. Scientists believe that it is probably genetically conditioned; the disroder is not completely understood yet. It is believed that due to genetic conditions, the ovaries produce more androgenic (male) hormones then normal and disturb the hormonal axis hypothalamus-pituitary gland-ovaries. As a result, many follicles in the ovaries are stimulated but none of them (or only a small number) actually develop into ovaa. Therefore, the follicles develop into small cysts (polycystic ovaries). Furthermore, because there is no ovulation (or it is rare) women diagnosed with PCOS experience irregular periods and sterility. Even if pregnancy occurs, there is an increased risk for miscarriage. It is also important to note that increased production of male hormones can cause hair growth, or "virilisation". During PCOS, other hormones such as insulin are also disturbed (not only limited to the sex hormones). A so called "insulin resistance" can develop during PCOS that manifests with obesity.


PCOS is diagnosed according to clinical manifestations (irregular cycles, sterility, obesity, virilisation), ultrasound examination (polycystic ovaries) and laboratory analyses (ratio LH/FSH higher then 2, normal DHEA, low progesterone on the 20-24th day of cycle).


Treatment is long and not always effective. There are 3 basic methods:


1. Temporarily blocking the axis hypothalamus-pituitary gland-ovaries with contraceptive pills (2-3 months) or with analogs of gonad-liberators (6-12 months);


2. Stimulating ovulation with clomifen, gonad-tropic hormones or GnRH, and


3. Surgical cuneiform ovarian resection (a less frequently used method).


Metformin (an anti-diabetic medication) is also used for correcting insulin resistance.